Entity Details

Name CDK1_Thr245
ID Q9GZM8
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1NDEL1Thr245GFGTSPLtPSARISAphosphorylation
up-regulates activity		12556484SIGNOR-274075
CyclinD1/CDK6NDEL1Thr245GFGTSPLtPSARISAphosphorylation
up-regulates activity		12796778SIGNOR-250652
CDK1NDEL1Thr245GFGTSPLtPSARISAphosphorylation
up-regulates activity		12556484SIGNOR-274072
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
NDEL1
PThr245		phosphorylation
up-regulates
→		NDEL112556484SIGNOR-274075
CyclinD1/CDK6phosphorylation
up-regulates
→
NDEL1
PThr245		phosphorylation
up-regulates
→		NDEL112796778SIGNOR-250652
CDK1phosphorylation
up-regulates
→
NDEL1
PThr245		phosphorylation
up-regulates
→		NDEL112556484SIGNOR-274072
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-274075
CyclinD1/CDK6phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-250652
CDK1phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-274072