Entity Details

Name MAPK1_Thr219
ID Q9GZM8
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5/CDK5R1NDEL1Thr219ASLSLPAtPVGKGTEphosphorylation
up-regulates activity		12796778SIGNOR-250678
MAPK1NDEL1Thr219ASLSLPAtPVGKGTEphosphorylation
up-regulates activity		12556484SIGNOR-274076
CDK1NDEL1Thr219ASLSLPAtPVGKGTEphosphorylation
up-regulates activity		12556484SIGNOR-274074
PPP4CNDEL1Thr219ASLSLPAtPVGKGTEdephosphorylation
down-regulates activity		18347064SIGNOR-248550
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5/CDK5R1phosphorylation
up-regulates
→
NDEL1
PThr219		phosphorylation
up-regulates
→		NDEL112796778SIGNOR-250678
MAPK1phosphorylation
up-regulates
→
NDEL1
PThr219		phosphorylation
up-regulates
→		NDEL112556484SIGNOR-274076
CDK1phosphorylation
up-regulates
→
NDEL1
PThr219		phosphorylation
up-regulates
→		NDEL112556484SIGNOR-274074
PPP4Cdephosphorylation
down-regulates
⊣
NDEL1
PThr219		dephosphorylation
up-regulates
→		NDEL118347064SIGNOR-248550
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5/CDK5R1phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-250678
MAPK1phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-274076
CDK1phosphorylation
→
up-regulates activity 		NDEL1SIGNOR-274074
PPP4Cdephosphorylation
→
down-regulates activity 		NDEL1SIGNOR-248550