| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | MCOLN1 | Ser559 | KFRRGSGsACSLLCC | phosphorylation down-regulates | 17988215 | SIGNOR-158950 |
| PRKACA | MCOLN1 | Ser557 | SGKFRRGsGSACSLL | phosphorylation down-regulates | 17988215 | SIGNOR-158946 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | MCOLN1 PSer559 | phosphorylation down-regulates ⊣ | MCOLN1 | 17988215 | SIGNOR-158950 |
| PRKACA | phosphorylation up-regulates → | MCOLN1 PSer557 | phosphorylation down-regulates ⊣ | MCOLN1 | 17988215 | SIGNOR-158946 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation down-regulates | MCOLN1 | SIGNOR-158950 |
| PRKACA | phosphorylation down-regulates | MCOLN1 | SIGNOR-158946 |
