| Name | NUAK2 |
| ID | Q9H093 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 53-303 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NUAK2 | PPP1R12A | – | phosphorylation down-regulates activity | 30622137 | SIGNOR-279081 | |
| NUAK2 | LAT | – | phosphorylation down-regulates activity | 30158528 | SIGNOR-280052 | |
| NUAK2 | LATS1 | Ser464 | NIPVRSNsFNNPLGN | phosphorylation down-regulates | 19927127 | SIGNOR-161796 |
| NUAK2 | WDR45 | – | phosphorylation up-regulates activity | 28561066 | SIGNOR-268481 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NUAK2 | phosphorylation up-regulates → | LATS1 PSer464 | phosphorylation down-regulates ⊣ | LATS1 | 19927127 | SIGNOR-161796 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| NUAK2 | phosphorylation → down-regulates activity | PPP1R12A | SIGNOR-279081 |
| NUAK2 | phosphorylation → down-regulates activity | LAT | SIGNOR-280052 |
| NUAK2 | phosphorylation down-regulates | LATS1 | SIGNOR-161796 |
| NUAK2 | phosphorylation → up-regulates activity | WDR45 | SIGNOR-268481 |