| Name | SIK2 |
| ID | Q9H0K1 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 20-271 PROSITE-ProRule
UBA 295-335 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK11 | SIK2 | Thr175 | KSGELLAtWCGSPPY | phosphorylation up-regulates | 14976552 | SIGNOR-122788 |
| SIK2 | SIK2 | Ser343 | RLKSHRSsFPVEQRL | phosphorylation up-regulates activity | 27478041 | SIGNOR-277268 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK11 | phosphorylation up-regulates → | SIK2 PThr175 | phosphorylation up-regulates → | SIK2 | 14976552 | SIGNOR-122788 |
| SIK2 | phosphorylation up-regulates → | SIK2 PSer343 | phosphorylation up-regulates → | SIK2 | 27478041 | SIGNOR-277268 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK11 | phosphorylation → up-regulates | SIK2 | SIGNOR-122788 |
| SIK2 | phosphorylation → up-regulates activity | SIK2 | SIGNOR-277268 |