Entity Details

Name CDT1
ID Q9H211
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK8CDT1Thr29PPKLACRtPSPARPAphosphorylation
down-regulates activity		21856198SIGNOR-278445
MAPK8CDT1Ser491GSCCTIMsPGEMEKHphosphorylation
up-regulates quantity by stabilization		21930785SIGNOR-276360
MAPK8CDT1Ser391LRSAAPSsPGSPRPAphosphorylation
up-regulates quantity by stabilization		21930785SIGNOR-276361
p38CDT1Ser391LRSAAPSsPGSPRPAphosphorylation
up-regulates quantity by stabilization		21930785SIGNOR-276362
p38CDT1Ser491GSCCTIMsPGEMEKHphosphorylation
up-regulates quantity by stabilization		21930785SIGNOR-276363
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK8phosphorylation
up-regulates
→
CDT1
PThr29		phosphorylation
down-regulates
⊣		CDT121856198SIGNOR-278445
MAPK8phosphorylation
up-regulates
→
CDT1
PSer491		phosphorylation
up-regulates
→		CDT121930785SIGNOR-276360
MAPK8phosphorylation
up-regulates
→
CDT1
PSer391		phosphorylation
up-regulates
→		CDT121930785SIGNOR-276361
p38phosphorylation
up-regulates
→
CDT1
PSer391		phosphorylation
up-regulates
→		CDT121930785SIGNOR-276362
p38phosphorylation
up-regulates
→
CDT1
PSer491		phosphorylation
up-regulates
→		CDT121930785SIGNOR-276363
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK8phosphorylation
→
down-regulates activity 		CDT1SIGNOR-278445
MAPK8phosphorylation
→
up-regulates quantity by stabilization 		CDT1SIGNOR-276360
MAPK8phosphorylation
→
up-regulates quantity by stabilization 		CDT1SIGNOR-276361
p38phosphorylation
→
up-regulates quantity by stabilization 		CDT1SIGNOR-276362
p38phosphorylation
→
up-regulates quantity by stabilization 		CDT1SIGNOR-276363