| Name | SMURF1 |
| ID | Q9HCE7 |
| Role | substrate |
| Enzymatic Domains |
C2 1-120 PROSITE-ProRule
WW 1 234-267 PROSITE-ProRule
WW 2 306-339 PROSITE-ProRule
HECT 420-757 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | SMURF1 | Thr145 | QTRDRIGtGGSVVDC | phosphorylation up-regulates activity | 27036023 | SIGNOR-279778 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | SMURF1 PThr145 | phosphorylation up-regulates → | SMURF1 | 27036023 | SIGNOR-279778 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → up-regulates activity | SMURF1 | SIGNOR-279778 |