Entity Details

Name	TDP1
ID	Q9NUW8
Role	substrate
Enzymatic Domains
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PRKDC	TDP1	Ser81 View in OncoXplorer	PKRQKSGsQEDLGWC	phosphorylation up-regulates	19851285	SIGNOR-188776
ATM	TDP1	Ser81 View in OncoXplorer	PKRQKSGsQEDLGWC	phosphorylation up-regulates	19851285	SIGNOR-188772

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PRKDC	phosphorylation up-regulates →	TDP1 PSer81	phosphorylation up-regulates →	TDP1	19851285	SIGNOR-188776
ATM	phosphorylation up-regulates →	TDP1 PSer81	phosphorylation up-regulates →	TDP1	19851285	SIGNOR-188772

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PRKDC	phosphorylation → up-regulates	TDP1	SIGNOR-188776
ATM	phosphorylation → up-regulates	TDP1	SIGNOR-188772