| Name | PLK2 |
| ID | Q9NYY3 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 82-334 PROSITE-ProRule
POLO box 1 503-581 PROSITE-ProRule
POLO box 2 601-685 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277791 |
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277805 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277791 |
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277805 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277791 |
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277805 |