| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277791 |
| DYRK1A | PLK2 | Ser358 | VPDFHLSsPAKNFFK | phosphorylation up-regulates quantity by stabilization | 37387444 | SIGNOR-277805 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277791 |
| DYRK1A | phosphorylation up-regulates → | PLK2 PSer358 | phosphorylation up-regulates → | PLK2 | 37387444 | SIGNOR-277805 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277791 |
| DYRK1A | phosphorylation → up-regulates quantity by stabilization | PLK2 | SIGNOR-277805 |