Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
GSK3B	CD274	Ser184	GKTTTTNsKREEKLF	phosphorylation down-regulates quantity by destabilization	27572267	SIGNOR-277275
GSK3B	CD274	Thr180	QVLSGKTtTTNSKRE	phosphorylation down-regulates quantity by destabilization	27572267	SIGNOR-277276
NEK2	CD274	Thr210	TNEIFYCtFRRLDPE	phosphorylation up-regulates quantity by stabilization	34315872	SIGNOR-277314
GSK3B	CD274	–		phosphorylation down-regulates quantity	27572267	SIGNOR-279047
GSK3A	CD274	Ser279 View in OncoXplorer	CGIQDTNsKKQSDTH	phosphorylation down-regulates quantity by destabilization	33879767	SIGNOR-277552
NEK2	CD274	Thr194	EEKLFNVtSTLRINT	phosphorylation up-regulates quantity by stabilization	34315872	SIGNOR-277315

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
GSK3B	phosphorylation up-regulates →	CD274 PSer184	phosphorylation down-regulates ⊣	CD274	27572267	SIGNOR-277275
GSK3B	phosphorylation up-regulates →	CD274 PThr180	phosphorylation down-regulates ⊣	CD274	27572267	SIGNOR-277276
NEK2	phosphorylation up-regulates →	CD274 PThr210	phosphorylation up-regulates →	CD274	34315872	SIGNOR-277314
GSK3A	phosphorylation up-regulates →	CD274 PSer279	phosphorylation down-regulates ⊣	CD274	33879767	SIGNOR-277552
NEK2	phosphorylation up-regulates →	CD274 PThr194	phosphorylation up-regulates →	CD274	34315872	SIGNOR-277315

Regulator	Mechanism/Effect	Target	SIGNOR-ID
GSK3B	phosphorylation down-regulates quantity by destabilization	CD274	SIGNOR-277275
GSK3B	phosphorylation down-regulates quantity by destabilization	CD274	SIGNOR-277276
NEK2	phosphorylation → up-regulates quantity by stabilization	CD274	SIGNOR-277314
GSK3B	phosphorylation → down-regulates quantity	CD274	SIGNOR-279047
GSK3A	phosphorylation down-regulates quantity by destabilization	CD274	SIGNOR-277552
NEK2	phosphorylation → up-regulates quantity by stabilization	CD274	SIGNOR-277315