Summary

Name CD274
Full Name Programmed cell death 1 ligand 1
Synonyms PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1 | B7H1, PDCD1L1, PDCD1LG1, PDL1
Primary ID Q9NZQ7
Links - -
Type protein
Relations 3
Function Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional activation CD274 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional activation CD274 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PDCD1 0.52
Publications: 1 Organism: Homo Sapiens