Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PAK5	SYNJ1	–		phosphorylation up-regulates activity	22371566	SIGNOR-263026
PAK5	AIFM1	Thr281	GAEVKSRtTLFRKIG	phosphorylation down-regulates activity	33867848	SIGNOR-279085
PAK5	TCF3	Ser39	NGKGRPAsLAGAQFG	phosphorylation up-regulates activity	26212009	SIGNOR-275653
PAK5	GATA1	Ser161	SSLPVPNsAYGGPDF	phosphorylation up-regulates activity	25726523	SIGNOR-275655
PAK5	GATA1	Ser161	SSLPVPNsAYGGPDF	phosphorylation up-regulates activity	25726523	SIGNOR-278296
PAK5	GATA1	Ser187	LNSAAYSsPKLRGTL	phosphorylation up-regulates activity	25726523	SIGNOR-275656
PAK5	GATA1	Ser187	LNSAAYSsPKLRGTL	phosphorylation up-regulates activity	25726523	SIGNOR-278297
PAK5	DDX5	Thr69	HPDLARRtAQEVETY	phosphorylation up-regulates quantity by stabilization	34936874	SIGNOR-275658
PAK5	RELA	–		phosphorylation up-regulates activity	29041983	SIGNOR-275657
PAK5	BAD	Ser75	EIRSRHSsYPAGTED	phosphorylation down-regulates activity	12897128	SIGNOR-250247
PAK5	PACSIN1	Ser346	SQAGDRGsVSSYDRG	phosphorylation up-regulates activity	22371566	SIGNOR-263025
PAK5	PAK5	His19	SGPSNFEhRVHTGFD	phosphorylation up-regulates activity	12860998	SIGNOR-250248
PAK5	PAK5	His22	SNFEHRVhTGFDPQE	phosphorylation up-regulates activity	12860998	SIGNOR-250249
PAK5	DNPEP	Ser119	VKRRSRRsQVGFQQV	phosphorylation down-regulates quantity by destabilization	31219614	SIGNOR-275651

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PAK5	phosphorylation up-regulates →	AIFM1 PThr281	phosphorylation down-regulates ⊣	AIFM1	33867848	SIGNOR-279085
PAK5	phosphorylation up-regulates →	TCF3 PSer39	phosphorylation up-regulates →	TCF3	26212009	SIGNOR-275653
PAK5	phosphorylation up-regulates →	GATA1 PSer161	phosphorylation up-regulates →	GATA1	25726523	SIGNOR-275655
PAK5	phosphorylation up-regulates →	GATA1 PSer161	phosphorylation up-regulates →	GATA1	25726523	SIGNOR-278296
PAK5	phosphorylation up-regulates →	GATA1 PSer187	phosphorylation up-regulates →	GATA1	25726523	SIGNOR-275656
PAK5	phosphorylation up-regulates →	GATA1 PSer187	phosphorylation up-regulates →	GATA1	25726523	SIGNOR-278297
PAK5	phosphorylation up-regulates →	DDX5 PThr69	phosphorylation up-regulates →	DDX5	34936874	SIGNOR-275658
PAK5	phosphorylation up-regulates →	BAD PSer75	phosphorylation down-regulates ⊣	BAD	12897128	SIGNOR-250247
PAK5	phosphorylation up-regulates →	PACSIN1 PSer346	phosphorylation up-regulates →	PACSIN1	22371566	SIGNOR-263025
PAK5	phosphorylation up-regulates →	PAK5 PHis19	phosphorylation up-regulates →	PAK5	12860998	SIGNOR-250248
PAK5	phosphorylation up-regulates →	PAK5 PHis22	phosphorylation up-regulates →	PAK5	12860998	SIGNOR-250249
PAK5	phosphorylation up-regulates →	DNPEP PSer119	phosphorylation down-regulates ⊣	DNPEP	31219614	SIGNOR-275651

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PAK5	phosphorylation → up-regulates activity	SYNJ1	SIGNOR-263026
PAK5	phosphorylation → down-regulates activity	AIFM1	SIGNOR-279085
PAK5	phosphorylation → up-regulates activity	TCF3	SIGNOR-275653
PAK5	phosphorylation → up-regulates activity	GATA1	SIGNOR-275655
PAK5	phosphorylation → up-regulates activity	GATA1	SIGNOR-278296
PAK5	phosphorylation → up-regulates activity	GATA1	SIGNOR-275656
PAK5	phosphorylation → up-regulates activity	GATA1	SIGNOR-278297
PAK5	phosphorylation → up-regulates quantity by stabilization	DDX5	SIGNOR-275658
PAK5	phosphorylation → up-regulates activity	RELA	SIGNOR-275657
PAK5	phosphorylation → down-regulates activity	BAD	SIGNOR-250247
PAK5	phosphorylation → up-regulates activity	PACSIN1	SIGNOR-263025
PAK5	phosphorylation → up-regulates activity	PAK5	SIGNOR-250248
PAK5	phosphorylation → up-regulates activity	PAK5	SIGNOR-250249
PAK5	phosphorylation down-regulates quantity by destabilization	DNPEP	SIGNOR-275651