Entity Details

Name FBXO5
ID Q9UKT4
Role substrate
Enzymatic Domains
F-box 250-296
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1FBXO5–phosphorylation
down-regulates		15469984SIGNOR-129813
CDK1FBXO5–phosphorylation
down-regulates quantity by destabilization		12791267SIGNOR-279143
SRCFBXO5Tyr142ALETSRLyEDSGYSSphosphorylation
up-regulates		20717963SIGNOR-167529
PLK1FBXO5–phosphorylation
down-regulates		16439210SIGNOR-142949
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
FBXO5
PTyr142		phosphorylation
up-regulates
→		FBXO520717963SIGNOR-167529
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
img/direct_inhibition.png
down-regulates 		FBXO5SIGNOR-129813
CDK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FBXO5SIGNOR-279143
SRCphosphorylation
→
up-regulates 		FBXO5SIGNOR-167529
PLK1phosphorylation
img/direct_inhibition.png
down-regulates 		FBXO5SIGNOR-142949