Entity Details

Name MACF1
ID Q9UPN3
Role substrate
Enzymatic Domains
Calponin-homology (CH) 1 78-181
PROSITE-ProRule
Calponin-homology (CH) 2 194-298
PROSITE-ProRule
SH3 868-925
PROSITE-ProRule
EF-hand 1 7041-7076
PROSITE-ProRule
EF-hand 2 7077-7112
PROSITE-ProRule
GAR 7117-7189
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GSK3BMACF1Ser7330RASSRRGsDASDFDLphosphorylation
down-regulates activity		21295697SIGNOR-264435
GSK3BMACF1Ser7230KPSSRAAsPTRSSSSphosphorylation
down-regulates activity		21295697SIGNOR-264428
GSK3BMACF1Ser7234RAASPTRsSSSASQSphosphorylation
down-regulates activity		21295697SIGNOR-264429
GSK3BMACF1Ser7326RAGSRASsRRGSDASphosphorylation
down-regulates activity		21295697SIGNOR-264434
GSK3BMACF1Ser7310ADPKKSAsRPGSRAGphosphorylation
down-regulates activity		21295697SIGNOR-264430
GSK3BMACF1Ser7314KSASRPGsRAGSRAGphosphorylation
down-regulates activity		21295697SIGNOR-264431
GSK3BMACF1Ser7322RAGSRAGsRASSRRGphosphorylation
down-regulates activity		21295697SIGNOR-264433
GSK3BMACF1Ser7318RPGSRAGsRAGSRASphosphorylation
down-regulates activity		21295697SIGNOR-264432
GSK3BMACF1Ser7222FRSRGRRsKPSSRAAphosphorylation
down-regulates activity		21295697SIGNOR-264426
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7330		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264435
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7230		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264428
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7234		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264429
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7326		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264434
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7310		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264430
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7314		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264431
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7322		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264433
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7318		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264432
GSK3Bphosphorylation
up-regulates
→
MACF1
PSer7222		phosphorylation
down-regulates
⊣		MACF121295697SIGNOR-264426
Regulator Mechanism/Effect Target SIGNOR-ID
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264435
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264428
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264429
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264434
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264430
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264431
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264433
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264432
GSK3Bphosphorylation
→
down-regulates activity 		MACF1SIGNOR-264426