| Name | MAPK8IP3 |
| ID | Q9UPT6 |
| Role | substrate |
| Enzymatic Domains |
RH1 12-100 PROSITE-ProRule
RH2 520-594 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | MAPK8IP3 | Thr286 | SVPSAAVtPLNESLQ | phosphorylation up-regulates | 15767678 | SIGNOR-134549 |
| MAPK10 | MAPK8IP3 | Thr286 | SVPSAAVtPLNESLQ | phosphorylation up-regulates | 15767678 | SIGNOR-134537 |
| MAPK10 | MAPK8IP3 | Thr275 | TTGTKSNtPTSSVPS | phosphorylation up-regulates | 15767678 | SIGNOR-134533 |
| MAPK8 | MAPK8IP3 | Thr265 | GQSSAAAtPSTTGTK | phosphorylation up-regulates | 15767678 | SIGNOR-134541 |
| JNK | MAPK8IP3 | – | phosphorylation up-regulates | 15767678 | SIGNOR-269984 | |
| ROCK1 | MAPK8IP3 | Ser364 | TRLDRTGsSPTQGIV | phosphorylation up-regulates | 15767678 | SIGNOR-134584 |
| MAPK8 | MAPK8IP3 | Thr275 | TTGTKSNtPTSSVPS | phosphorylation up-regulates | 15767678 | SIGNOR-134545 |
| MAPK9 | MAPK8IP3 | Thr286 | SVPSAAVtPLNESLQ | phosphorylation up-regulates | 15767678 | SIGNOR-134576 |
| MAPK9 | MAPK8IP3 | Thr275 | TTGTKSNtPTSSVPS | phosphorylation up-regulates | 15767678 | SIGNOR-134572 |
| MAPK9 | MAPK8IP3 | Thr265 | GQSSAAAtPSTTGTK | phosphorylation up-regulates | 15767678 | SIGNOR-134568 |
| ROCK1 | MAPK8IP3 | Ser314 | RAREKRDsRNMEVQV | phosphorylation up-regulates | 15767678 | SIGNOR-134580 |
| ROCK1 | MAPK8IP3 | Ser365 | RLDRTGSsPTQGIVN | phosphorylation up-regulates | 15767678 | SIGNOR-134588 |
| MAPK10 | MAPK8IP3 | Thr265 | GQSSAAAtPSTTGTK | phosphorylation up-regulates | 15767678 | SIGNOR-134529 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | phosphorylation up-regulates → | MAPK8IP3 PThr286 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134549 |
| MAPK10 | phosphorylation up-regulates → | MAPK8IP3 PThr286 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134537 |
| MAPK10 | phosphorylation up-regulates → | MAPK8IP3 PThr275 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134533 |
| MAPK8 | phosphorylation up-regulates → | MAPK8IP3 PThr265 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134541 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer364 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134584 |
| MAPK8 | phosphorylation up-regulates → | MAPK8IP3 PThr275 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134545 |
| MAPK9 | phosphorylation up-regulates → | MAPK8IP3 PThr286 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134576 |
| MAPK9 | phosphorylation up-regulates → | MAPK8IP3 PThr275 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134572 |
| MAPK9 | phosphorylation up-regulates → | MAPK8IP3 PThr265 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134568 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer314 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134580 |
| ROCK1 | phosphorylation up-regulates → | MAPK8IP3 PSer365 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134588 |
| MAPK10 | phosphorylation up-regulates → | MAPK8IP3 PThr265 | phosphorylation up-regulates → | MAPK8IP3 | 15767678 | SIGNOR-134529 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK8 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134549 |
| MAPK10 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134537 |
| MAPK10 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134533 |
| MAPK8 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134541 |
| JNK | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-269984 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134584 |
| MAPK8 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134545 |
| MAPK9 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134576 |
| MAPK9 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134572 |
| MAPK9 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134568 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134580 |
| ROCK1 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134588 |
| MAPK10 | phosphorylation → up-regulates | MAPK8IP3 | SIGNOR-134529 |