Summary

Name MAPK8IP3
Full Name C-Jun-amino-terminal kinase-interacting protein 3
Synonyms JIP-3, JNK-interacting protein 3, JNK MAP kinase scaffold protein 3, Mitogen-activated protein kinase 8-interacting protein 3 | JIP3, KIAA1066
Primary ID Q9UPT6
Links - -
Type protein
Relations 19
Function The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation MAPK8IP3 0.14
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation MAPK8IP3 0.22
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation MAPK8IP3 0.22
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation MAPK8IP3 0.22
Publications: 3 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding MAPK10 0.28
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding MAPK8 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding MAPK9 0.22
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding MAP2K7 0.28
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding MAP3K11 0.22
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ up-regulates img/direct-activation.png binding MAP2K4 0.28
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding MAP3K1 0.14
Publications: 1 Organism: Homo Sapiens