| Name | USP24 |
| ID | Q9UPU5 |
| Role | substrate |
| Enzymatic Domains |
UBA 3-44 PROSITE-ProRule
USP 1689-2042 |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | USP24 | Ser1616 | NSHSPAGsAAISQQD | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275605 |
| CDK1 | USP24 | Ser2604 | HLQQGSEsPMMIGEL | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275603 |
| CyclinB/CDK1 | USP24 | Ser1616 | NSHSPAGsAAISQQD | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275611 |
| ATM | USP24 | – | phosphorylation up-regulates activity | 25578727 | SIGNOR-280043 | |
| CDK1 | USP24 | Ser2047 | QRVSDQNsPVLPKKS | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275604 |
| CyclinB/CDK1 | USP24 | Ser2047 | QRVSDQNsPVLPKKS | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275610 |
| CyclinB/CDK1 | USP24 | Ser2604 | HLQQGSEsPMMIGEL | phosphorylation down-regulates quantity by destabilization | 27991932 | SIGNOR-275609 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | USP24 PSer1616 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275605 |
| CDK1 | phosphorylation up-regulates → | USP24 PSer2604 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275603 |
| CyclinB/CDK1 | phosphorylation up-regulates → | USP24 PSer1616 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275611 |
| CDK1 | phosphorylation up-regulates → | USP24 PSer2047 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275604 |
| CyclinB/CDK1 | phosphorylation up-regulates → | USP24 PSer2047 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275610 |
| CyclinB/CDK1 | phosphorylation up-regulates → | USP24 PSer2604 | phosphorylation down-regulates ⊣ | USP24 | 27991932 | SIGNOR-275609 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275605 |
| CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275603 |
| CyclinB/CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275611 |
| ATM | phosphorylation → up-regulates activity | USP24 | SIGNOR-280043 |
| CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275604 |
| CyclinB/CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275610 |
| CyclinB/CDK1 | phosphorylation down-regulates quantity by destabilization | USP24 | SIGNOR-275609 |