| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | AKT3 | Ser474 | HFPQFSYsASGRE | dephosphorylation down-regulates activity | 18160256 | SIGNOR-248609 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2CB | dephosphorylation down-regulates ⊣ | AKT3 PSer474 | dephosphorylation up-regulates → | AKT3 | 18160256 | SIGNOR-248609 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2CB | dephosphorylation → down-regulates activity | AKT3 | SIGNOR-248609 |
