| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TESK2 | CFL2 | Ser3 | sGVTVNDE | phosphorylation down-regulates activity | 11418599 | SIGNOR-246711 |
| TESK1 | CFL2 | Ser3 | sGVTVNDE | phosphorylation down-regulates activity | 11418599 | SIGNOR-246719 |
| LIMK1 | CFL2 | Ser3 | sGVTVNDE | phosphorylation down-regulates activity | 9655398 | SIGNOR-58596 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TESK2 | phosphorylation up-regulates → | CFL2 PSer3 | phosphorylation down-regulates ⊣ | CFL2 | 11418599 | SIGNOR-246711 |
| TESK1 | phosphorylation up-regulates → | CFL2 PSer3 | phosphorylation down-regulates ⊣ | CFL2 | 11418599 | SIGNOR-246719 |
| LIMK1 | phosphorylation up-regulates → | CFL2 PSer3 | phosphorylation down-regulates ⊣ | CFL2 | 9655398 | SIGNOR-58596 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TESK2 | phosphorylation → down-regulates activity | CFL2 | SIGNOR-246711 |
| TESK1 | phosphorylation → down-regulates activity | CFL2 | SIGNOR-246719 |
| LIMK1 | phosphorylation → down-regulates activity | CFL2 | SIGNOR-58596 |