Entity Details

Name IKBKG
ID Q9Y6K9
Role kinase
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IKBKGNFKBIASer32LLDDRHDsGLDSMKDphosphorylation
down-regulates activity		18412279SIGNOR-280462
IKBKGRELASer536SGDEDFSsIADMDFSphosphorylation
up-regulates activity		15489227SIGNOR-129947
IKBKGNfKb-p65/p50–phosphorylation
up-regulates		15489227SIGNOR-217382
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IKBKGphosphorylation
up-regulates
→
NFKBIA
PSer32		phosphorylation
down-regulates
⊣		NFKBIA18412279SIGNOR-280462
IKBKGphosphorylation
up-regulates
→
RELA
PSer536		phosphorylation
up-regulates
→		RELA15489227SIGNOR-129947
Regulator Mechanism/Effect Target SIGNOR-ID
IKBKGphosphorylation
→
down-regulates activity 		NFKBIASIGNOR-280462
IKBKGphosphorylation
→
up-regulates activity 		RELASIGNOR-129947
IKBKGphosphorylation
→
up-regulates 		NfKb-p65/p50SIGNOR-217382