Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSNK1A1	FOXO	Ser321	NSNASTVsGRLSPIM	phosphorylation down-regulates	20110348	SIGNOR-252900
MAPK14	FOXO	Ser7	sPAPLSPL	phosphorylation up-regulates	22128155	SIGNOR-252960
AKT1	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252844
AKT2	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	19188143	SIGNOR-252867
PIM1	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates	18593906	SIGNOR-252967
AKT1	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates activity	19188143	SIGNOR-252848
PIM1	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates	18593906	SIGNOR-252966
PRKAA1	FOXO	–		phosphorylation up-regulates activity	17900900	SIGNOR-252983
AKT	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252821
IKK-complex	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates	15084260	SIGNOR-252950
AKT3	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates	19188143	SIGNOR-252878
IKBKB	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates	19188143	SIGNOR-252947
AKT	FOXO	Ser197	APRRRAAsMDSSSKL	phosphorylation down-regulates	16272144	SIGNOR-252828
AKT1	FOXO	–		phosphorylation down-regulates	18394876	SIGNOR-252859
AKT2	FOXO	Ser256	SPRRRAAsMDNNSKF	phosphorylation down-regulates activity	10377430	SIGNOR-252871
CSNK1A1	FOXO	Ser318	SRTNSNAsTVSGRLS	phosphorylation down-regulates	20110348	SIGNOR-252899
AKT	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252823
AKT	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	19188143	SIGNOR-252826
IKK-complex	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates quantity by destabilization	19188143	SIGNOR-252951
AKT3	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252874
MAPK1	FOXO	Ser425	TKGSGLGsPTSSFNS	phosphorylation down-regulates quantity by destabilization	18204439	SIGNOR-252959
MAPK1	FOXO	Ser344	QDDDAPLsPMLYSSS	phosphorylation down-regulates quantity by destabilization	18204439	SIGNOR-252958
AKT1	FOXO	–		phosphorylation down-regulates quantity by destabilization	21440011	SIGNOR-252858
AKT3	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates	19188143	SIGNOR-252877
AMPK	FOXO	Ser626	SLECDMEsIIRSELM	phosphorylation up-regulates activity	17711846	SIGNOR-252884
AKT1	FOXO	Thr24	LPRPRSCtWPLPRPE	phosphorylation down-regulates	10377430	SIGNOR-252857
RALA	FOXO	Thr451	PIPKALGtPVLTPPT	phosphorylation up-regulates activity	11689711	SIGNOR-252984
PKN1	FOXO	Ser256	SPRRRAAsMDNNSKF	phosphorylation down-regulates	12560069	SIGNOR-252968
AKT2	FOXO	Thr32	QSRPRSCtWPLPRPE	phosphorylation down-regulates activity	16272144	SIGNOR-252870
MAPK8	FOXO	Thr451	PIPKALGtPVLTPPT	phosphorylation up-regulates	15538382	SIGNOR-252964
CSNK1A1	FOXO	–		phosphorylation down-regulates	19188143	SIGNOR-252898
PRKAA1	FOXO	Ser588	QTLSDSLsGSSLYST	phosphorylation up-regulates activity	17711846	SIGNOR-252978
AKT1	FOXO	Ser256	SPRRRAAsMDNNSKF	phosphorylation down-regulates	10377430	SIGNOR-252856
Gbeta	FOXO	–		phosphorylation down-regulates quantity by destabilization	19282669	SIGNOR-270020
AKT	FOXO	Ser319	TFRPRTSsNASTISG	phosphorylation down-regulates	11237865	SIGNOR-252835
AKT1	FOXO	Ser262	TFRPRSSsNASSVST	phosphorylation down-regulates activity	10217147	SIGNOR-252862
AKT1	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates activity	19188143	SIGNOR-252850
PRKAA1	FOXO	Ser626	SLECDMEsIIRSELM	phosphorylation up-regulates activity	17711846	SIGNOR-252979
AMPK	FOXO	–		phosphorylation up-regulates	17900900	SIGNOR-252886
PRKAA1	FOXO	–		phosphorylation up-regulates	17900900	SIGNOR-252981
AKT	FOXO	Thr24	LPRPRSCtWPLPRPE	phosphorylation down-regulates	10377430	SIGNOR-252832
AKT	FOXO	Ser262	TFRPRSSsNASSVST	phosphorylation down-regulates	16272144	SIGNOR-252829
SGK1	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates activity	11154281	SIGNOR-252989
AKT	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates activity	19188143	SIGNOR-252827
JNK	FOXO	Thr455	ALGTPVLtPPTEAAS	phosphorylation up-regulates	20959475	SIGNOR-252956
AMPK	FOXO	Ser399	DNITLPPsQPSPTGG	phosphorylation up-regulates activity	17711846	SIGNOR-252880
AKT1	FOXO	Ser197	APRRRAAsMDSSSKL	phosphorylation down-regulates	16272144	SIGNOR-252853
JNK	FOXO	Thr451	PIPKALGtPVLTPPT	phosphorylation up-regulates	20959475	SIGNOR-252955
AKT1	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252846
DYRK1A	FOXO	–		phosphorylation down-regulates	19188143	SIGNOR-252905
AKT1	FOXO	–		phosphorylation down-regulates	21620960	SIGNOR-252847
AKT3	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252875
AKT	FOXO	–		phosphorylation down-regulates	18394876	SIGNOR-252834
CDK2	FOXO	Ser249	EGGKSGKsPRRRAAS	phosphorylation down-regulates	17038621	SIGNOR-252892
PRKAA1	FOXO	Ser399	DNITLPPsQPSPTGG	phosphorylation up-regulates activity	17711846	SIGNOR-252975
PIM	FOXO	–		phosphorylation down-regulates	18593906	SIGNOR-259427
AKT	FOXO	Ser197	APRRRAAsMDSSSKL	phosphorylation down-regulates activity	10217147	SIGNOR-252838
AKT	FOXO	Ser256	SPRRRAAsMDNNSKF	phosphorylation down-regulates	10377430	SIGNOR-252831
AKT	FOXO	–		phosphorylation down-regulates quantity by destabilization	21440011	SIGNOR-252833
AKT	FOXO	–		phosphorylation down-regulates	21620960	SIGNOR-252824
AMPK	FOXO	–		phosphorylation up-regulates activity	17900900	SIGNOR-252889
AKT3	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252876
SGK2	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates activity	11154281	SIGNOR-252991
AKT2	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates activity	19188143	SIGNOR-252868
JNK	FOXO	Ser230	PEGATPTsPVGHFAK	phosphorylation up-regulates	20959475	SIGNOR-252953
SGK2	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	11154281	SIGNOR-252990
AKT	FOXO	–		phosphorylation down-regulates	21798082	SIGNOR-252820
AKT3	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates	19188143	SIGNOR-252879
DYRK1A	FOXO	Ser329	STISGRLsPIMTEQD	phosphorylation down-regulates activity	11311120	SIGNOR-252909
AMPK	FOXO	Ser413	GLMQRSSsFPYTTKG	phosphorylation up-regulates activity	17711846	SIGNOR-252881
SGK3	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	11154281	SIGNOR-252992
DYRK1A	FOXO	Ser330	RLSPIMAsTELDEVQ	phosphorylation down-regulates	19188143	SIGNOR-252907
AKT2	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates activity	19188143	SIGNOR-252869
PPP2CA	FOXO	Ser253	APRRRAVsMDNSNKY	dephosphorylation up-regulates	18593906	SIGNOR-252971
CSNK1G1	FOXO	Ser325	SSNASTIsGRLSPIM	phosphorylation down-regulates activity	11980723	SIGNOR-252902
AKT1	FOXO	Ser319	TFRPRTSsNASTISG	phosphorylation down-regulates	11237865	SIGNOR-252860
AKT1	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	19188143	SIGNOR-252849
AKT	FOXO	Thr32	QSRPRSCtWPLPRPE	phosphorylation down-regulates	16272144	SIGNOR-252830
AKT1	FOXO	–		phosphorylation down-regulates activity	18423396	SIGNOR-252851
CHUK	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates	15084260	SIGNOR-252893
STK4	FOXO	Ser212	SSAGWKNsIRHNLSL	phosphorylation up-regulates	22898666	SIGNOR-252998
AMPK	FOXO	Ser588	QTLSDSLsGSSLYST	phosphorylation up-regulates activity	17711846	SIGNOR-252883
AKT1	FOXO	Thr32	QSRPRSCtWPLPRPE	phosphorylation down-regulates	16272144	SIGNOR-252855
MAPK3	FOXO	Ser294	QLSKWPGsPTSRSSD	phosphorylation down-regulates quantity by destabilization	19282669	SIGNOR-252961
AKT2	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252865
STK4	FOXO	–		phosphorylation up-regulates	18394876	SIGNOR-253002
STK4	FOXO	Ser212	SSAGWKNsIRHNLSL	phosphorylation up-regulates	18394876	SIGNOR-252999
PRKAA1	FOXO	Ser555	RALSNSVsNMGLSES	phosphorylation up-regulates activity	17711846	SIGNOR-252977
AKT2	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252863
CSNK1G1	FOXO	Ser322	PRTSSNAsTISGRLS	phosphorylation down-regulates activity	11980723	SIGNOR-252901
IKBKB	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates	15084260	SIGNOR-252948
AKT2	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252864
SGK1	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates activity	11154281	SIGNOR-252988
IKBKE	FOXO	Ser644	GLDFNFDsLISTQNV	phosphorylation down-regulates	23691078	SIGNOR-252949
AKT2	FOXO	Thr24	LPRPRSCtWPLPRPE	phosphorylation down-regulates activity	10377430	SIGNOR-252872
AKT	FOXO	Thr32	QSRPRSCtWPLQRPE	phosphorylation down-regulates activity	19188143	SIGNOR-252825
AKT2	FOXO	Thr32	QSRPRSCtWPLPRPE	phosphorylation down-regulates activity	11313479	SIGNOR-252873
MAPK8	FOXO	Thr455	ALGTPVLtPPTEAAS	phosphorylation up-regulates	15538382	SIGNOR-252965
PPP2CA	FOXO	Ser253	APRRRAVsMDNSNKY	dephosphorylation up-regulates	20110348	SIGNOR-252973
DUSP6	FOXO	–		dephosphorylation up-regulates	22521266	SIGNOR-252903
MAPK3	FOXO	Ser425	TKGSGLGsPTSSFNS	phosphorylation down-regulates quantity by destabilization	19282669	SIGNOR-252963
PRKAA1	FOXO	Thr179	SSPDKRLtLSQIYEW	phosphorylation up-regulates activity	17711846	SIGNOR-252980
AKT1	FOXO	Ser197	APRRRAAsMDSSSKL	phosphorylation down-regulates activity	10217147	SIGNOR-252861
PRKAA1	FOXO	Ser413	GLMQRSSsFPYTTKG	phosphorylation up-regulates activity	17711846	SIGNOR-252976
STK4	FOXO	Ser209	SSAGWKNsIRHNLSL	phosphorylation up-regulates	22898666	SIGNOR-253000
AKT	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252822
AKT	FOXO	–		phosphorylation down-regulates activity	18423396	SIGNOR-252836
MAPK1	FOXO	Ser294	QLSKWPGsPTSRSSD	phosphorylation down-regulates quantity by destabilization	18204439	SIGNOR-252957
AKT2	FOXO	–		phosphorylation down-regulates activity	21620960	SIGNOR-252866
AMPK	FOXO	Thr179	SSPDKRLtLSQIYEW	phosphorylation up-regulates activity	17711846	SIGNOR-252885
STK4	FOXO	Ser209	SSAGWKNsIRHNLSL	phosphorylation up-regulates	18394876	SIGNOR-253001
MAPK3	FOXO	Ser344	QDDDAPLsPMLYSSS	phosphorylation down-regulates quantity by destabilization	19282669	SIGNOR-252962
AMPK	FOXO	Ser555	RALSNSVsNMGLSES	phosphorylation up-regulates activity	17711846	SIGNOR-252882
AKT	FOXO	Ser262	TFRPRSSsNASSVST	phosphorylation down-regulates activity	10217147	SIGNOR-252839
JNK	FOXO	Thr227	PAPPEGAtPTSPVGH	phosphorylation up-regulates	20959475	SIGNOR-252954
ERK1/2	FOXO	–		phosphorylation down-regulates quantity by destabilization	19282669	SIGNOR-270146
AKT1	FOXO	Ser262	TFRPRSSsNASSVST	phosphorylation down-regulates	16272144	SIGNOR-252854
CDK1	FOXO	Ser249	EGGKSGKsPRRRAAS	phosphorylation down-regulates	18408765	SIGNOR-252890
CDK2	FOXO	–		phosphorylation down-regulates	19188143	SIGNOR-252891
RALA	FOXO	Thr455	ALGTPVLtPPTEAAS	phosphorylation up-regulates activity	11689711	SIGNOR-252985
AKT1	FOXO	–		phosphorylation down-regulates activity	21798082	SIGNOR-252841
DYRK1A	FOXO	Ser330	RLSPIMAsTELDEVQ	phosphorylation down-regulates activity	19188143	SIGNOR-252906
PPP2CA	FOXO	Thr32	QSRPRSCtWPLQRPE	dephosphorylation up-regulates	20110348	SIGNOR-252974
AKT1	FOXO	Ser315	DFRSRTNsNASTVSG	phosphorylation down-regulates quantity by destabilization	19951971	SIGNOR-252845
AKT1	FOXO	–		phosphorylation down-regulates	21798082	SIGNOR-252843
SGK1	FOXO	Ser253	APRRRAVsMDNSNKY	phosphorylation down-regulates activity	11154281	SIGNOR-252987

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSNK1A1	phosphorylation up-regulates →	FOXO PSer321	phosphorylation down-regulates ⊣	FOXO	20110348	SIGNOR-252900
MAPK14	phosphorylation up-regulates →	FOXO PSer7	phosphorylation up-regulates →	FOXO	22128155	SIGNOR-252960
AKT1	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252844
AKT2	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252867
PIM1	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	18593906	SIGNOR-252967
AKT1	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252848
PIM1	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	18593906	SIGNOR-252966
AKT	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252821
IKK-complex	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	15084260	SIGNOR-252950
AKT3	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252878
IKBKB	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252947
AKT	phosphorylation up-regulates →	FOXO PSer197	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252828
AKT2	phosphorylation up-regulates →	FOXO PSer256	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252871
CSNK1A1	phosphorylation up-regulates →	FOXO PSer318	phosphorylation down-regulates ⊣	FOXO	20110348	SIGNOR-252899
AKT	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252823
AKT	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252826
IKK-complex	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252951
AKT3	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252874
MAPK1	phosphorylation up-regulates →	FOXO PSer425	phosphorylation down-regulates ⊣	FOXO	18204439	SIGNOR-252959
MAPK1	phosphorylation up-regulates →	FOXO PSer344	phosphorylation down-regulates ⊣	FOXO	18204439	SIGNOR-252958
AKT3	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252877
AMPK	phosphorylation up-regulates →	FOXO PSer626	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252884
AKT1	phosphorylation up-regulates →	FOXO PThr24	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252857
RALA	phosphorylation up-regulates →	FOXO PThr451	phosphorylation up-regulates →	FOXO	11689711	SIGNOR-252984
PKN1	phosphorylation up-regulates →	FOXO PSer256	phosphorylation down-regulates ⊣	FOXO	12560069	SIGNOR-252968
AKT2	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252870
MAPK8	phosphorylation up-regulates →	FOXO PThr451	phosphorylation up-regulates →	FOXO	15538382	SIGNOR-252964
PRKAA1	phosphorylation up-regulates →	FOXO PSer588	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252978
AKT1	phosphorylation up-regulates →	FOXO PSer256	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252856
AKT	phosphorylation up-regulates →	FOXO PSer319	phosphorylation down-regulates ⊣	FOXO	11237865	SIGNOR-252835
AKT1	phosphorylation up-regulates →	FOXO PSer262	phosphorylation down-regulates ⊣	FOXO	10217147	SIGNOR-252862
AKT1	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252850
PRKAA1	phosphorylation up-regulates →	FOXO PSer626	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252979
AKT	phosphorylation up-regulates →	FOXO PThr24	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252832
AKT	phosphorylation up-regulates →	FOXO PSer262	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252829
SGK1	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252989
AKT	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252827
JNK	phosphorylation up-regulates →	FOXO PThr455	phosphorylation up-regulates →	FOXO	20959475	SIGNOR-252956
AMPK	phosphorylation up-regulates →	FOXO PSer399	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252880
AKT1	phosphorylation up-regulates →	FOXO PSer197	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252853
JNK	phosphorylation up-regulates →	FOXO PThr451	phosphorylation up-regulates →	FOXO	20959475	SIGNOR-252955
AKT1	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252846
AKT3	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252875
CDK2	phosphorylation up-regulates →	FOXO PSer249	phosphorylation down-regulates ⊣	FOXO	17038621	SIGNOR-252892
PRKAA1	phosphorylation up-regulates →	FOXO PSer399	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252975
AKT	phosphorylation up-regulates →	FOXO PSer197	phosphorylation down-regulates ⊣	FOXO	10217147	SIGNOR-252838
AKT	phosphorylation up-regulates →	FOXO PSer256	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252831
AKT3	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252876
SGK2	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252991
AKT2	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252868
JNK	phosphorylation up-regulates →	FOXO PSer230	phosphorylation up-regulates →	FOXO	20959475	SIGNOR-252953
SGK2	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252990
AKT3	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252879
DYRK1A	phosphorylation up-regulates →	FOXO PSer329	phosphorylation down-regulates ⊣	FOXO	11311120	SIGNOR-252909
AMPK	phosphorylation up-regulates →	FOXO PSer413	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252881
SGK3	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252992
DYRK1A	phosphorylation up-regulates →	FOXO PSer330	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252907
AKT2	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252869
PPP2CA	dephosphorylation down-regulates ⊣	FOXO PSer253	dephosphorylation down-regulates ⊣	FOXO	18593906	SIGNOR-252971
CSNK1G1	phosphorylation up-regulates →	FOXO PSer325	phosphorylation down-regulates ⊣	FOXO	11980723	SIGNOR-252902
AKT1	phosphorylation up-regulates →	FOXO PSer319	phosphorylation down-regulates ⊣	FOXO	11237865	SIGNOR-252860
AKT1	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252849
AKT	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252830
CHUK	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	15084260	SIGNOR-252893
STK4	phosphorylation up-regulates →	FOXO PSer212	phosphorylation up-regulates →	FOXO	22898666	SIGNOR-252998
AMPK	phosphorylation up-regulates →	FOXO PSer588	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252883
AKT1	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252855
MAPK3	phosphorylation up-regulates →	FOXO PSer294	phosphorylation down-regulates ⊣	FOXO	19282669	SIGNOR-252961
AKT2	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252865
STK4	phosphorylation up-regulates →	FOXO PSer212	phosphorylation up-regulates →	FOXO	18394876	SIGNOR-252999
PRKAA1	phosphorylation up-regulates →	FOXO PSer555	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252977
AKT2	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252863
CSNK1G1	phosphorylation up-regulates →	FOXO PSer322	phosphorylation down-regulates ⊣	FOXO	11980723	SIGNOR-252901
IKBKB	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	15084260	SIGNOR-252948
AKT2	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252864
SGK1	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252988
IKBKE	phosphorylation up-regulates →	FOXO PSer644	phosphorylation down-regulates ⊣	FOXO	23691078	SIGNOR-252949
AKT2	phosphorylation up-regulates →	FOXO PThr24	phosphorylation down-regulates ⊣	FOXO	10377430	SIGNOR-252872
AKT	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252825
AKT2	phosphorylation up-regulates →	FOXO PThr32	phosphorylation down-regulates ⊣	FOXO	11313479	SIGNOR-252873
MAPK8	phosphorylation up-regulates →	FOXO PThr455	phosphorylation up-regulates →	FOXO	15538382	SIGNOR-252965
PPP2CA	dephosphorylation down-regulates ⊣	FOXO PSer253	dephosphorylation down-regulates ⊣	FOXO	20110348	SIGNOR-252973
MAPK3	phosphorylation up-regulates →	FOXO PSer425	phosphorylation down-regulates ⊣	FOXO	19282669	SIGNOR-252963
PRKAA1	phosphorylation up-regulates →	FOXO PThr179	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252980
AKT1	phosphorylation up-regulates →	FOXO PSer197	phosphorylation down-regulates ⊣	FOXO	10217147	SIGNOR-252861
PRKAA1	phosphorylation up-regulates →	FOXO PSer413	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252976
STK4	phosphorylation up-regulates →	FOXO PSer209	phosphorylation up-regulates →	FOXO	22898666	SIGNOR-253000
AKT	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252822
MAPK1	phosphorylation up-regulates →	FOXO PSer294	phosphorylation down-regulates ⊣	FOXO	18204439	SIGNOR-252957
AMPK	phosphorylation up-regulates →	FOXO PThr179	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252885
STK4	phosphorylation up-regulates →	FOXO PSer209	phosphorylation up-regulates →	FOXO	18394876	SIGNOR-253001
MAPK3	phosphorylation up-regulates →	FOXO PSer344	phosphorylation down-regulates ⊣	FOXO	19282669	SIGNOR-252962
AMPK	phosphorylation up-regulates →	FOXO PSer555	phosphorylation up-regulates →	FOXO	17711846	SIGNOR-252882
AKT	phosphorylation up-regulates →	FOXO PSer262	phosphorylation down-regulates ⊣	FOXO	10217147	SIGNOR-252839
JNK	phosphorylation up-regulates →	FOXO PThr227	phosphorylation up-regulates →	FOXO	20959475	SIGNOR-252954
AKT1	phosphorylation up-regulates →	FOXO PSer262	phosphorylation down-regulates ⊣	FOXO	16272144	SIGNOR-252854
CDK1	phosphorylation up-regulates →	FOXO PSer249	phosphorylation down-regulates ⊣	FOXO	18408765	SIGNOR-252890
RALA	phosphorylation up-regulates →	FOXO PThr455	phosphorylation up-regulates →	FOXO	11689711	SIGNOR-252985
DYRK1A	phosphorylation up-regulates →	FOXO PSer330	phosphorylation down-regulates ⊣	FOXO	19188143	SIGNOR-252906
PPP2CA	dephosphorylation down-regulates ⊣	FOXO PThr32	dephosphorylation down-regulates ⊣	FOXO	20110348	SIGNOR-252974
AKT1	phosphorylation up-regulates →	FOXO PSer315	phosphorylation down-regulates ⊣	FOXO	19951971	SIGNOR-252845
SGK1	phosphorylation up-regulates →	FOXO PSer253	phosphorylation down-regulates ⊣	FOXO	11154281	SIGNOR-252987

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSNK1A1	phosphorylation down-regulates	FOXO	SIGNOR-252900
MAPK14	phosphorylation → up-regulates	FOXO	SIGNOR-252960
AKT1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252844
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252867
PIM1	phosphorylation down-regulates	FOXO	SIGNOR-252967
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252848
PIM1	phosphorylation down-regulates	FOXO	SIGNOR-252966
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252983
AKT	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252821
IKK-complex	phosphorylation down-regulates	FOXO	SIGNOR-252950
AKT3	phosphorylation down-regulates	FOXO	SIGNOR-252878
IKBKB	phosphorylation down-regulates	FOXO	SIGNOR-252947
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252828
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252859
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252871
CSNK1A1	phosphorylation down-regulates	FOXO	SIGNOR-252899
AKT	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252823
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252826
IKK-complex	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252951
AKT3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252874
MAPK1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252959
MAPK1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252958
AKT1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252858
AKT3	phosphorylation down-regulates	FOXO	SIGNOR-252877
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252884
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252857
RALA	phosphorylation → up-regulates activity	FOXO	SIGNOR-252984
PKN1	phosphorylation down-regulates	FOXO	SIGNOR-252968
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252870
MAPK8	phosphorylation → up-regulates	FOXO	SIGNOR-252964
CSNK1A1	phosphorylation down-regulates	FOXO	SIGNOR-252898
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252978
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252856
Gbeta	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-270020
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252835
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252862
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252850
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252979
AMPK	phosphorylation → up-regulates	FOXO	SIGNOR-252886
PRKAA1	phosphorylation → up-regulates	FOXO	SIGNOR-252981
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252832
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252829
SGK1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252989
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252827
JNK	phosphorylation → up-regulates	FOXO	SIGNOR-252956
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252880
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252853
JNK	phosphorylation → up-regulates	FOXO	SIGNOR-252955
AKT1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252846
DYRK1A	phosphorylation down-regulates	FOXO	SIGNOR-252905
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252847
AKT3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252875
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252834
CDK2	phosphorylation down-regulates	FOXO	SIGNOR-252892
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252975
PIM	phosphorylation down-regulates	FOXO	SIGNOR-259427
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252838
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252831
AKT	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252833
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252824
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252889
AKT3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252876
SGK2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252991
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252868
JNK	phosphorylation → up-regulates	FOXO	SIGNOR-252953
SGK2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252990
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252820
AKT3	phosphorylation down-regulates	FOXO	SIGNOR-252879
DYRK1A	phosphorylation → down-regulates activity	FOXO	SIGNOR-252909
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252881
SGK3	phosphorylation → down-regulates activity	FOXO	SIGNOR-252992
DYRK1A	phosphorylation down-regulates	FOXO	SIGNOR-252907
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252869
PPP2CA	dephosphorylation → up-regulates	FOXO	SIGNOR-252971
CSNK1G1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252902
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252860
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252849
AKT	phosphorylation down-regulates	FOXO	SIGNOR-252830
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252851
CHUK	phosphorylation down-regulates	FOXO	SIGNOR-252893
STK4	phosphorylation → up-regulates	FOXO	SIGNOR-252998
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252883
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252855
MAPK3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252961
AKT2	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252865
STK4	phosphorylation → up-regulates	FOXO	SIGNOR-253002
STK4	phosphorylation → up-regulates	FOXO	SIGNOR-252999
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252977
AKT2	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252863
CSNK1G1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252901
IKBKB	phosphorylation down-regulates	FOXO	SIGNOR-252948
AKT2	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252864
SGK1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252988
IKBKE	phosphorylation down-regulates	FOXO	SIGNOR-252949
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252872
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252825
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252873
MAPK8	phosphorylation → up-regulates	FOXO	SIGNOR-252965
PPP2CA	dephosphorylation → up-regulates	FOXO	SIGNOR-252973
DUSP6	dephosphorylation → up-regulates	FOXO	SIGNOR-252903
MAPK3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252963
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252980
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252861
PRKAA1	phosphorylation → up-regulates activity	FOXO	SIGNOR-252976
STK4	phosphorylation → up-regulates	FOXO	SIGNOR-253000
AKT	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252822
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252836
MAPK1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252957
AKT2	phosphorylation → down-regulates activity	FOXO	SIGNOR-252866
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252885
STK4	phosphorylation → up-regulates	FOXO	SIGNOR-253001
MAPK3	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252962
AMPK	phosphorylation → up-regulates activity	FOXO	SIGNOR-252882
AKT	phosphorylation → down-regulates activity	FOXO	SIGNOR-252839
JNK	phosphorylation → up-regulates	FOXO	SIGNOR-252954
ERK1/2	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-270146
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252854
CDK1	phosphorylation down-regulates	FOXO	SIGNOR-252890
CDK2	phosphorylation down-regulates	FOXO	SIGNOR-252891
RALA	phosphorylation → up-regulates activity	FOXO	SIGNOR-252985
AKT1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252841
DYRK1A	phosphorylation → down-regulates activity	FOXO	SIGNOR-252906
PPP2CA	dephosphorylation → up-regulates	FOXO	SIGNOR-252974
AKT1	phosphorylation down-regulates quantity by destabilization	FOXO	SIGNOR-252845
AKT1	phosphorylation down-regulates	FOXO	SIGNOR-252843
SGK1	phosphorylation → down-regulates activity	FOXO	SIGNOR-252987