| Name | AKT1_Ser197 |
| ID | SIGNOR-PF27 |
| Role | residue |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates | 16272144 | SIGNOR-252828 |
| AKT1 | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates | 16272144 | SIGNOR-252853 |
| AKT | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates activity | 10217147 | SIGNOR-252838 |
| AKT1 | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates activity | 10217147 | SIGNOR-252861 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 16272144 | SIGNOR-252828 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 16272144 | SIGNOR-252853 |
| AKT | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 10217147 | SIGNOR-252838 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 10217147 | SIGNOR-252861 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT | phosphorylation![]() down-regulates | FOXO | SIGNOR-252828 |
| AKT1 | phosphorylation![]() down-regulates | FOXO | SIGNOR-252853 |
| AKT | phosphorylation → down-regulates activity | FOXO | SIGNOR-252838 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252861 |