Entity Details

Name AKT2_Ser315
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT3FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates		19188143SIGNOR-252878
AKT1FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates activity		19188143SIGNOR-252850
SGK1FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates activity		11154281SIGNOR-252989
AKTFOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates activity		19188143SIGNOR-252827
AKT3FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates quantity by destabilization		19951971SIGNOR-252875
AKT2FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates activity		19188143SIGNOR-252868
AKT2FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates quantity by destabilization		19951971SIGNOR-252864
AKTFOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates quantity by destabilization		19951971SIGNOR-252822
AKT1FOXOSer315DFRSRTNsNASTVSGphosphorylation
down-regulates quantity by destabilization		19951971SIGNOR-252845
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT3phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19188143SIGNOR-252878
AKT1phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19188143SIGNOR-252850
SGK1phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO11154281SIGNOR-252989
AKTphosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19188143SIGNOR-252827
AKT3phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19951971SIGNOR-252875
AKT2phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19188143SIGNOR-252868
AKT2phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19951971SIGNOR-252864
AKTphosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19951971SIGNOR-252822
AKT1phosphorylation
up-regulates
→
FOXO
PSer315		phosphorylation
down-regulates
⊣		FOXO19951971SIGNOR-252845
Regulator Mechanism/Effect Target SIGNOR-ID
AKT3phosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252878
AKT1phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252850
SGK1phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252989
AKTphosphorylation
→
down-regulates activity 		FOXOSIGNOR-252827
AKT3phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252875
AKT2phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252868
AKT2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252864
AKTphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252822
AKT1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252845