Entity Details

Name AKT_Ser197
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1FOXOSer197APRRRAAsMDSSSKLphosphorylation
down-regulates		16272144SIGNOR-252853
AKTFOXOSer197APRRRAAsMDSSSKLphosphorylation
down-regulates activity		10217147SIGNOR-252838
AKT1FOXOSer197APRRRAAsMDSSSKLphosphorylation
down-regulates activity		10217147SIGNOR-252861
AKTFOXOSer197APRRRAAsMDSSSKLphosphorylation
down-regulates		16272144SIGNOR-252828
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
FOXO
PSer197		phosphorylation
down-regulates
⊣		FOXO16272144SIGNOR-252853
AKTphosphorylation
up-regulates
→
FOXO
PSer197		phosphorylation
down-regulates
⊣		FOXO10217147SIGNOR-252838
AKT1phosphorylation
up-regulates
→
FOXO
PSer197		phosphorylation
down-regulates
⊣		FOXO10217147SIGNOR-252861
AKTphosphorylation
up-regulates
→
FOXO
PSer197		phosphorylation
down-regulates
⊣		FOXO16272144SIGNOR-252828
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252853
AKTphosphorylation
→
down-regulates activity 		FOXOSIGNOR-252838
AKT1phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252861
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252828