Entity Details

Name AKT_Ser256
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1FOXOSer256SPRRRAAsMDNNSKFphosphorylation
down-regulates		10377430SIGNOR-252856
AKTFOXOSer256SPRRRAAsMDNNSKFphosphorylation
down-regulates		10377430SIGNOR-252831
AKT2FOXOSer256SPRRRAAsMDNNSKFphosphorylation
down-regulates activity		10377430SIGNOR-252871
PKN1FOXOSer256SPRRRAAsMDNNSKFphosphorylation
down-regulates		12560069SIGNOR-252968
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
FOXO
PSer256		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252856
AKTphosphorylation
up-regulates
→
FOXO
PSer256		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252831
AKT2phosphorylation
up-regulates
→
FOXO
PSer256		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252871
PKN1phosphorylation
up-regulates
→
FOXO
PSer256		phosphorylation
down-regulates
⊣		FOXO12560069SIGNOR-252968
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252856
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252831
AKT2phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252871
PKN1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252968