Entity Details

Name AKT_Thr24
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT1FOXOThr24LPRPRSCtWPLPRPEphosphorylation
down-regulates		10377430SIGNOR-252857
AKTFOXOThr24LPRPRSCtWPLPRPEphosphorylation
down-regulates		10377430SIGNOR-252832
AKT2FOXOThr24LPRPRSCtWPLPRPEphosphorylation
down-regulates activity		10377430SIGNOR-252872
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT1phosphorylation
up-regulates
→
FOXO
PThr24		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252857
AKTphosphorylation
up-regulates
→
FOXO
PThr24		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252832
AKT2phosphorylation
up-regulates
→
FOXO
PThr24		phosphorylation
down-regulates
⊣		FOXO10377430SIGNOR-252872
Regulator Mechanism/Effect Target SIGNOR-ID
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252857
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		FOXOSIGNOR-252832
AKT2phosphorylation
→
down-regulates activity 		FOXOSIGNOR-252872