| Name | AMPK_Ser399 |
| ID | SIGNOR-PF27 |
| Role | residue |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | FOXO | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252880 |
| PRKAA1 | FOXO | Ser399 | DNITLPPsQPSPTGG | phosphorylation up-regulates activity | 17711846 | SIGNOR-252975 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | phosphorylation up-regulates → | FOXO PSer399 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252880 |
| PRKAA1 | phosphorylation up-regulates → | FOXO PSer399 | phosphorylation up-regulates → | FOXO | 17711846 | SIGNOR-252975 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AMPK | phosphorylation → up-regulates activity | FOXO | SIGNOR-252880 |
| PRKAA1 | phosphorylation → up-regulates activity | FOXO | SIGNOR-252975 |