| Name | CHUK_Ser644 |
| ID | SIGNOR-PF27 |
| Role | residue |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates | 15084260 | SIGNOR-252893 |
| IKBKB | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates | 15084260 | SIGNOR-252948 |
| IKBKE | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates | 23691078 | SIGNOR-252949 |
| IKK-complex | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates | 15084260 | SIGNOR-252950 |
| IKBKB | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates | 19188143 | SIGNOR-252947 |
| IKK-complex | FOXO | Ser644 | GLDFNFDsLISTQNV | phosphorylation down-regulates quantity by destabilization | 19188143 | SIGNOR-252951 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 15084260 | SIGNOR-252893 |
| IKBKB | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 15084260 | SIGNOR-252948 |
| IKBKE | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 23691078 | SIGNOR-252949 |
| IKK-complex | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 15084260 | SIGNOR-252950 |
| IKBKB | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252947 |
| IKK-complex | phosphorylation up-regulates → | FOXO PSer644 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252951 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHUK | phosphorylation![]() down-regulates | FOXO | SIGNOR-252893 |
| IKBKB | phosphorylation![]() down-regulates | FOXO | SIGNOR-252948 |
| IKBKE | phosphorylation![]() down-regulates | FOXO | SIGNOR-252949 |
| IKK-complex | phosphorylation![]() down-regulates | FOXO | SIGNOR-252950 |
| IKBKB | phosphorylation![]() down-regulates | FOXO | SIGNOR-252947 |
| IKK-complex | phosphorylation![]() down-regulates quantity by destabilization | FOXO | SIGNOR-252951 |