| Name | MAPK1_Ser425 |
| ID | SIGNOR-PF27 |
| Role | residue |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | FOXO | Ser425 | TKGSGLGsPTSSFNS | phosphorylation down-regulates quantity by destabilization | 19282669 | SIGNOR-252963 |
| MAPK1 | FOXO | Ser425 | TKGSGLGsPTSSFNS | phosphorylation down-regulates quantity by destabilization | 18204439 | SIGNOR-252959 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | FOXO PSer425 | phosphorylation down-regulates ⊣ | FOXO | 19282669 | SIGNOR-252963 |
| MAPK1 | phosphorylation up-regulates → | FOXO PSer425 | phosphorylation down-regulates ⊣ | FOXO | 18204439 | SIGNOR-252959 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation![]() down-regulates quantity by destabilization | FOXO | SIGNOR-252963 |
| MAPK1 | phosphorylation![]() down-regulates quantity by destabilization | FOXO | SIGNOR-252959 |