Entity Details

Name MAPK3_Ser425
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3FOXOSer425TKGSGLGsPTSSFNSphosphorylation
down-regulates quantity by destabilization		19282669SIGNOR-252963
MAPK1FOXOSer425TKGSGLGsPTSSFNSphosphorylation
down-regulates quantity by destabilization		18204439SIGNOR-252959
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
FOXO
PSer425		phosphorylation
down-regulates
⊣		FOXO19282669SIGNOR-252963
MAPK1phosphorylation
up-regulates
→
FOXO
PSer425		phosphorylation
down-regulates
⊣		FOXO18204439SIGNOR-252959
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252963
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		FOXOSIGNOR-252959