Entity Details

Name MAPK8_Thr451
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RALAFOXOThr451PIPKALGtPVLTPPTphosphorylation
up-regulates activity		11689711SIGNOR-252984
MAPK8FOXOThr451PIPKALGtPVLTPPTphosphorylation
up-regulates		15538382SIGNOR-252964
JNKFOXOThr451PIPKALGtPVLTPPTphosphorylation
up-regulates		20959475SIGNOR-252955
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RALAphosphorylation
up-regulates
→
FOXO
PThr451		phosphorylation
up-regulates
→		FOXO11689711SIGNOR-252984
MAPK8phosphorylation
up-regulates
→
FOXO
PThr451		phosphorylation
up-regulates
→		FOXO15538382SIGNOR-252964
JNKphosphorylation
up-regulates
→
FOXO
PThr451		phosphorylation
up-regulates
→		FOXO20959475SIGNOR-252955
Regulator Mechanism/Effect Target SIGNOR-ID
RALAphosphorylation
→
up-regulates activity 		FOXOSIGNOR-252984
MAPK8phosphorylation
→
up-regulates 		FOXOSIGNOR-252964
JNKphosphorylation
→
up-regulates 		FOXOSIGNOR-252955