Entity Details

Name MAPK8_Thr455
ID SIGNOR-PF27
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RALAFOXOThr455ALGTPVLtPPTEAASphosphorylation
up-regulates activity		11689711SIGNOR-252985
JNKFOXOThr455ALGTPVLtPPTEAASphosphorylation
up-regulates		20959475SIGNOR-252956
MAPK8FOXOThr455ALGTPVLtPPTEAASphosphorylation
up-regulates		15538382SIGNOR-252965
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RALAphosphorylation
up-regulates
→
FOXO
PThr455		phosphorylation
up-regulates
→		FOXO11689711SIGNOR-252985
JNKphosphorylation
up-regulates
→
FOXO
PThr455		phosphorylation
up-regulates
→		FOXO20959475SIGNOR-252956
MAPK8phosphorylation
up-regulates
→
FOXO
PThr455		phosphorylation
up-regulates
→		FOXO15538382SIGNOR-252965
Regulator Mechanism/Effect Target SIGNOR-ID
RALAphosphorylation
→
up-regulates activity 		FOXOSIGNOR-252985
JNKphosphorylation
→
up-regulates 		FOXOSIGNOR-252956
MAPK8phosphorylation
→
up-regulates 		FOXOSIGNOR-252965