Summary

Name CSKMT
Full Name Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial
Synonyms CS-KMT, Methyltransferase-like protein 12, mitochondrial | METTL12
Primary ID A8MUP2
Links - -
Type protein
Relations 2
Function Protein-lysine methyltransferase that selectively trimethylates citrate synthase (CS) in mitochondria (PubMed:28391595, PubMed:28887308). Seems to conduct trimethylation in a highly distributive manner rather than in a processive manner, and thus introduces a single methly group per binding event (PubMed:28887308).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png methylation CS 0.2
Publications: 2