| + |
G6PD | up-regulates quantity
chemical modification
|
6-O-phosphono-D-glucono-1,5-lactone |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267051 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24769394 |
G6PD catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconate and concomitantly reduces NADP+ to NADPH, which is the rate-limiting and primary control step of the NADPH-generating portion in the PPP. Thus, G6PD acts as a guardian of cellular redox potential during oxidative stress |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Pentose phosphate pathway |
| + |
PGLS | down-regulates quantity
chemical modification
|
6-O-phosphono-D-glucono-1,5-lactone |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267057 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31586547 |
The second enzyme in the oxiPPP, 6-phosphogluconolactonase (PGLS), converts 6PGL to 6-phosphogluconate (6PG). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Pentose phosphate pathway |
| + |
alpha-D-glucose 6-phosphate(2-) | up-regulates quantity
precursor of
|
6-O-phosphono-D-glucono-1,5-lactone |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267049 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24769394 |
G6PD catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconate and concomitantly reduces NADP+ to NADPH, which is the rate-limiting and primary control step of the NADPH-generating portion in the PPP. Thus, G6PD acts as a guardian of cellular redox potential during oxidative stress |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Pentose phosphate pathway |
| + |
6-O-phosphono-D-glucono-1,5-lactone | up-regulates quantity
precursor of
|
6-phospho-D-gluconate |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267056 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31586547 |
The second enzyme in the oxiPPP, 6-phosphogluconolactonase (PGLS), converts 6PGL to 6-phosphogluconate (6PG). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Pentose phosphate pathway |