Relation Results

Summary

Name Trp-tRNA(Trp)
Synonyms L-Tryptophanyl-tRNA(Trp) (KEGG COMPOUND), Trp-tRNA(Trp) (CBN)
IUPAC
Formula (C5H8O6P)nC26H31N7O11PR2
Primary ID CHEBI:29159
Type small molecule
Relations 6
Pathways Translation elongation and termination

Viewer

Type: Score: Layout: SPV 
0.80.80.80.80.80.8EEF1A1P5Trp-tRNA(Trp)tryptophantRNA(Trp)WARS1EEF1A1EEF1A2

Relations

Regulator
Mechanism
target
score
+ up-regulates img/direct-activation.png relocalization Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-269557 Homo sapiens
pmid sentence
During protein synthesis, eEF1A binds to and delivers aminoacylated tRNAs (aa-tRNAs) to the elongating ribosome (Fig. 1). GTP bound to eEF1A is hydrolyzed upon codon-anticodon match between an aa-tRNA in the A site of the ribosome and mRNA bound to the ribosome.
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png precursor of Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-270516 Homo sapiens
pmid sentence
Aminoacyl-tRNA synthetases (aaRSs)1 are a family of ancient enzymes that catalyze amino acid activation by ATP and the subsequent aminoacylation to its cognate tRNA. Alternative splicing produces two forms of hTrpRS in human cells: full-length hTrpRS (residues 1-471) and mini-hTrpRS (residues 48-471)
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png precursor of Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-270515 Homo sapiens
pmid sentence
Aminoacyl-tRNA synthetases (aaRSs)1 are a family of ancient enzymes that catalyze amino acid activation by ATP and the subsequent aminoacylation to its cognate tRNA. Alternative splicing produces two forms of hTrpRS in human cells: full-length hTrpRS (residues 1-471) and mini-hTrpRS (residues 48-471)
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png chemical modification Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-270514 Homo sapiens
pmid sentence
Aminoacyl-tRNA synthetases (aaRSs)1 are a family of ancient enzymes that catalyze amino acid activation by ATP and the subsequent aminoacylation to its cognate tRNA. Alternative splicing produces two forms of hTrpRS in human cells: full-length hTrpRS (residues 1-471) and mini-hTrpRS (residues 48-471)
Publications: 1 Organism: Homo Sapiens
Pathways:Translation elongation and termination
+ up-regulates img/direct-activation.png relocalization Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-269517 Homo sapiens
pmid sentence
During protein synthesis, eEF1A binds to and delivers aminoacylated tRNAs (aa-tRNAs) to the elongating ribosome (Fig. 1). GTP bound to eEF1A is hydrolyzed upon codon-anticodon match between an aa-tRNA in the A site of the ribosome and mRNA bound to the ribosome.
Publications: 1 Organism: Homo Sapiens
Pathways:Translation elongation and termination
+ up-regulates img/direct-activation.png relocalization Trp-tRNA(Trp) 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-269537 Homo sapiens
pmid sentence
During protein synthesis, eEF1A binds to and delivers aminoacylated tRNAs (aa-tRNAs) to the elongating ribosome (Fig. 1). GTP bound to eEF1A is hydrolyzed upon codon-anticodon match between an aa-tRNA in the A site of the ribosome and mRNA bound to the ribosome.
Publications: 1 Organism: Homo Sapiens
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