3.0
Summary
| Name |  FXYD1View Modifications |
| Full Name | Phospholemman |
| Synonyms | FXYD domain-containing ion transport regulator 1 | PLM |
| Primary ID | O00168 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. |
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phosphorylation
phosphorylation