3.0
Summary
| Name |  SOCS6
|
| Full Name | Suppressor of cytokine signaling 6 |
| Synonyms | SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4 | CIS4, SOCS4 |
| Primary ID | O14544 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor. |
ubiquitination