4.0
Summary
| Name |  POLR1C
|
| Full Name | DNA-directed RNA polymerases I and III subunit RPAC1 |
| Synonyms | DNA-directed RNA polymerase I subunit C, RNA polymerases I and III subunit AC1, AC40, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RPA40, RPA39, RPC40 | POLR1E |
| Primary ID | O15160 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | POLR1C | form complex 
binding
|
RNA Polymerase I | 0.913 |
| Publications: | 1 | |||
| + | POLR1C | form complex
binding
|
RNA Polymerase III | 0.881 |
| Publications: | 1 | Organism: | Homo Sapiens | |