Name
|
MAP3K13
|
Full Name |
Mitogen-activated protein kinase kinase kinase 13 |
Synonyms |
Leucine zipper-bearing kinase, Mixed lineage kinase, MLK | LZK |
Primary ID |
O43283 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B. |