Summary

Name MAP3K13
Full Name Mitogen-activated protein kinase kinase kinase 13
Synonyms Leucine zipper-bearing kinase, Mixed lineage kinase, MLK | LZK
Primary ID O43283
Links - -
Type protein
Relations 1
Function Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation MAP2K7 0.562
Publications: 1 Organism: Homo Sapiens