+ |
PNCK | up-regulates
phosphorylation
|
EIF4G3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-197190 |
Ser1156 |
NTFMRGGsSKDLLDN |
Homo sapiens |
|
pmid |
sentence |
22514323 |
Here we report that activity-dependent translational initiation in cultured rat hippocampal neurons is enhanced by camki-mediated phosphorylation of ser1156 in eukaryotic initiation factor eif4gii (4gii). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CAMK1 |
phosphorylation
|
EIF4G3 |
0.486 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-250613 |
Ser1156 |
NTFMRGGsSKDLLDN |
Homo sapiens |
|
pmid |
sentence |
14507913 |
Endogenous eIF4GII immunoprecipitated from HEK293T cells was phosphorylated by CaMKI, in vitro as was a recombinant fragment of eIF4GII encompassing the central and C-terminal regions. The latter phosphorylation occurred with favorable kinetics (Km = 1 microm; kcat = 1.8 s-1) at a single site, Ser1156, located in a segment of eIF4GII aligning with the phosphoregion of eIF4GI. Phosphopeptide mapping and back phosphorylation experiments revealed [Ca2+]i-dependent, CaMKI site-specific, eIF4GII phosphorylation in vivo. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
CAMK1G | up-regulates
phosphorylation
|
EIF4G3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-197149 |
Ser1156 |
NTFMRGGsSKDLLDN |
Homo sapiens |
|
pmid |
sentence |
22514323 |
Here we report that activity-dependent translational initiation in cultured rat hippocampal neurons is enhanced by camki-mediated phosphorylation of ser1156 in eukaryotic initiation factor eif4gii (4gii). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EIF3_complex | up-regulates activity
stabilization
|
EIF4G3 |
0.395 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269157 |
|
|
Homo sapiens |
|
pmid |
sentence |
17581632 |
EIF3 plays many functions in initiation complex formation. It interacts with eIF1, eIF5, eIF4B and eIF4G, and the direct interaction between eIF3 and eIF4G may serve as a bridge between the 40S ribosomal subunit and eIF4F-bound mRNA (Hershey and Merrick, 2000). eIF3 stabilizes the binding of the eIF2-GTP-Met-tRNAiMet ternary complex to the 40S subunit |
|
Publications: |
1 |
Organism: |
Homo Sapiens |