3.0
Summary
| Name |  URI1View Modifications |
| Full Name | Unconventional prefoldin RPB5 interactor 1 |
| Synonyms | Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RNA polymerase II subunit 5-mediating protein, RPB5-mediating protein | C19orf2, NNX3, PPP1R19, RMP, URI |
| Primary ID | O94763 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.; FUNCTION |
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