Relation Results

Name	GDF11
Full Name	Growth/differentiation factor 11
Synonyms	GDF-11, Bone morphogenetic protein 11, BMP-11 \| BMP11
Primary ID	O95390
Links	- -
Type	protein
Relations	4
Function	Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).