Summary

Name CFD
Full Name Complement factor D
Synonyms Adipsin, C3 convertase activator, Properdin factor D | DF, PFD
Primary ID P00746
Links - -
Type protein
Relations 2
Function Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png cleavage CFB 0.794
Publications: 2 Organism: Homo Sapiens
Tissue: Blood