| + |
C1QA | form complex 
binding
|
Complement C1q |
0.628 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263390 |
|
|
in vitro |
|
| pmid |
sentence |
| 29449492 |
C1q comprises 18 polypeptide chains; three chains of C1q-A, -B, and -C trimerize to form six collagen-like triple helices connected to six globular (trimeric) ligand-recognition (gC1q) modules (fig. S1B) (1). |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
C1QBP | down-regulates activity 
binding
|
C1QA |
0.392 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-263402 |
|
|
|
|
| pmid |
sentence |
| 28018340 |
Previous studies have shown that gC1qR inhibits aggregated IgG-mediated complement activation by binding to the gC1q site on C1q, thereby preventing IgG from binding to the gh’s (28), suggesting that the binding sites for gC1qR and IgG on C1q may be identical or at least overlapping. |
|
| Publications: |
1 |
3.0
C1QA
- 
- 