Summary

Name C1QB
Full Name Complement C1q subcomponent subunit B
Synonyms C1QB_HUMAN |
Primary ID P02746
Links - -
Type protein
Relations 2
Function C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ C1QBform complex img/form-complex.png binding Complement C1q 0.629
Publications: 1 Organism: In Vitro
+ C1QBPdown-regulates activity img/direct_inhibition.png binding C1QB 0.346
Publications: 1