Name CHRM2
Full Name Muscarinic acetylcholine receptor M2
Synonyms ACM2_HUMAN
Primary ID P08172
Links - -
Type protein
Relations 1
Function The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.



Regulator Mechanism target score
+ up-regulates img/indirect-activation.png unknown GNAO1 0.29
Publications: 1 Organism: Homo Sapiens