Summary

Name SNRPC
Full Name U1 small nuclear ribonucleoprotein C
Synonyms U1 snRNP C, U1-C, U1C |
Primary ID P09234
Links - -
Type protein
Relations 1
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.

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Relations

Regulator Mechanism target score ℹ
+ SNRPCform complex img/form-complex.png binding U1 snRNP complex 0.899
Publications: 1 Organism: Homo Sapiens