Summary

Name TPM1
Full Name Tropomyosin alpha-1 chain
Synonyms Alpha-tropomyosin, Tropomyosin-1 | C15orf13, TMSA
Primary ID P09493
Links - -
Type protein
Relations 2
Function Binds to actin filaments in muscle and non-muscle cells (PubMed:23170982). Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982). Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation TPM1 0.281
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation TPM1 0.2
Publications: 1 Organism: In Vitro