| + |
TGFB3 | up-regulates 
binding
|
TGFB3 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-148611 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16885528 |
The active form of tgf-b is a dimer stabilized by hydrophobic interactions and usually further strengthened by an intersubunit disulfide bridge |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TGFB3 | up-regulates
binding
|
TGFBR2 |
0.861 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-104798 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11157754 |
T?RII Is known to bind the isoforms tgf??1 And tgf??3. Binding of these ligands causes recruitment of the type i receptor (t?RI) into a signalling receptor complex followed by activation of t?RI Through transphosphorylation |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TGFB3 | up-regulates 
|
Angiogenesis |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-252284 |
|
|
|
|
| pmid |
sentence |
| 17326328 |
More than a dozen different proteins have been identified as angiogenic activators, including vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, transforming growth factor (TGF)-α, TGF-β, tumor necrosis factor (TNF)-α, platelet-derived endothelial growth factor, granulocyte colony-stimulating factor, placental growth factor, interleukin-8, hepatocyte growth factor, and epidermal growth factor |
|
| Publications: |
1 |
| + |
FOXE1 | up-regulates quantity by expression
transcriptional regulation
|
TGFB3 |
0.357 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254174 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 21177256 |
The MSX1 and TGF-β3 up-regulation in response to FOXE1 at both transcriptional and translational levels and the recruitment of FOXE1 to specific binding motifs, together with the transactivation of the promoters of these genes, indicate that MSX1 and TGF-β3 are direct FOXE1 targets. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
TGFB3
- 
- 